动物饲养与模型构建

本公司提供动物饲养与模型构建，欢迎咨询洽谈！

用于生物医药研究的动物模型具备以下五个特点：

1. There can be substantial asymmetry in the number of similarities and differences between the model and the target. In theory, the model and the target only need to have a single feature in common, but there can be any number of differences. This means that useful models can sometimes be highly abstract, such as a mathematical equation or computer simulation.

2. There necessarily are some differences between the model and the target otherwise the model would not be a model. Some of the differences are extremely important as they allow us to do things with the model which would not be possible with a human. Mice are widely used because they are small, prolific, and we can manipulate their genetics in ways not possible with humans. These differences from humans make them more, not less, valuable as models of humans for some applications. But this also makes them unsuitable for other applications such as heart surgery.

3. Models are highly specific to a particular study. Strains of mice and rats which develop cancer, heart disease, diabetes or neurological diseases could be of great interest in the study of these diseases, but these animals would probably be unsuitable for regulatory toxicology where long-lived strains are usually required. Thus, it is impossible to say whether "the rat' is a good or bad model of humans without specifying the context of the proposed study.

4. Models need to be validated. Research using animal models usually aims to predict a response in humans. When a new treatment for a particular disease or condition is developed in animals clinical trials will normally show whether or not the model was valid. The one exception is in testing industrial and environmental chemicals for their toxicity, where deliberate exposure of humans is not ethically acceptable.

5. Models are subject to improvement through further research. A lot of animal research is aimed at understanding the animal as a potential model for particular human conditions, without being too precise as to what those conditions might be. Models are not just found. They need to be developed, and this requires an understanding of the biology of the species and the effects of various interventions such as inactivating specific genes or manipulating the environment. As our understanding   increases, so the chance of choosing the most appropriate models for a specific disease increases.

资料来源于animal-research info

佰而林生物科技有限公司，是一家由归国留学专家创办的专注于生命科学领域的高科技企业。公司提供覆盖分子生物学、细胞生物学、免疫学等领域的实验室产品、生物技术服务以及专业生物统计分析等咨询服务，致力于为客户在生命领域探索创造有利条件。经过三年的高速发展，已经在全国重点城市都成立了办事处，与当地科研院校保持着广泛的合作。

佰而林提供覆盖临床医学、分子生物学、细胞生物学、免疫学、病理学等生命科学领域的生物技术服务，包括荧光定量PCR、免疫印迹、ELISA、流式细胞术、免疫组化、动物造模等。公司技术人员均具备本科以上专业背景，为客户提供强大的技术保障。

佰而林广州实验中心拥有强大的技术团队，公司员工研究生以上学历占比30%，本科以上学历占比100%。公司配备先进科研仪器设备如：AKTA蛋白纯化系统、流式细胞仪、激光共聚焦显微镜、液-质联用（LC-MS）系统、luminex200、制备兼分析型高效液相色谱仪、酶联斑点图像自动分析仪、实时荧光定量PCR仪等。

佰而林的服务宗旨是提升客户的研发技术质量，降低客户的研发总体成本，缩短客户的研发整体周期。让我们专业的技术团队，为您的成功，助一臂之力。