Naturethink 技术文章

1167 次微生理系统产生的剪切力可减少关节炎3D模型中TNF-α介导的软骨损伤 2025-4-1
Microphysiological System-Generated Physiological Shear Forces Reduce TNF-α-Mediated Cartilage Damage in a 3D Model of ArthritisKeywords: TNF‐α; articular cartilage br
1210 次牙髓干细胞调节真皮成纤维细胞的炎症小体通路和胶原沉积 2025-3-31
Dental Pulp Stem Cells Modulate Inflammasome Pathway and Collagen Deposition of Dermal FibroblastsKeywords: dental pulp stem cells; fibroblasts; fibrosis; inflammasome; inflammatio
1185 次 Tenascin-X 介导血流诱导的 EndMT 和动脉粥样硬化抑制 2025-3-25
Tenascin-X Mediates Flow-Induced Suppression of EndMT and AtherosclerosisKeywords: atherosclerosis; carotid arteries; endothelium; hemodynamics; inflammation; transforming growth f
996 次芥菜籽过敏原 Sina1 激活肠上皮细胞与树突状细胞 2025-3-24
Mustard seed major allergen Sin a1 activates intestinal epithelial cells and also dendritic cells that drive type 2 immune responsesKWS：Mustard seed；Sin a1；intestinal epithelial
923 次动脉粥样硬化和内皮机械转导 2025-3-17
Atherosclerosis and endothelial mechanotransduction: current knowledge and models for future researchKeywords: atherosclerosis; endothelial cell glycocalyx; mechanotransduction; sh
1208 次 HEG1 通过调节内皮细胞中KLF2/4 表达来预防动脉粥样硬化 2025-3-17
HEG1 Protects Against Atherosclerosis by Regulating Stable Flow-Induced KLF2/4 Expression in Endothelial CellsKeywords: KLF2/4; atherosclerosis; endothelial cells; heart-of-glass 1
1195 次 JAG1-NOTCH4 机械感应驱动动脉粥样硬化 2025-3-10
JAG1-NOTCH4 mechanosensing drives atherosclerosisKWS：JAG1-NOTCH4；mechanosensing；atherosclerosis血流产生机械剪切应力，通过改变血管内皮细胞（ECs）的生理机能，对血管功能产生深远影响
1463 次辣椒素借 SIRT3 抑制铁死亡维持线粒体稳态，减轻呼吸机致肺损伤 2025-3-10
Capsaicin mitigates ventilator-induced lung injury by suppressing ferroptosis and maintaining mitochondrial redox homeostasis through SIRT3-dependent mechanismsKeywords: Capsaicin;
1406 次肿瘤相关炎性细胞因子增强了骨髓间充质基质细胞对中性粒细胞的保护 2025-3-3
Protection of neutrophils by bone marrow mesenchymal stromal cells is enhanced by tumor-associated inflammatory cytokinesKeywords: G-CSF; inflammation; mesenchymal stromal/stem cel
1209 次机械力调节脂肪干细胞的旁分泌功能促进大鼠皮肤扩张 2025-3-3
Mechanical force regulates the paracrine functions of ADSCs to assist skin expansion in ratsKeywords: ADSC paracrine; Angiogenesis; Collagen secretion; Mechanical force; Skin expan
1350 次 GDF15 调节唑来膦酸诱导的牙周膜成纤维细胞的高炎机械反应 2025-2-24
GDF15 Modulates the Zoledronic-Acid-Induced Hyperinflammatory Mechanoresponse of Periodontal Ligament FibroblastsKeywords: DNA damage response; GDF15; inflammatory mechanoresponse;
1293 次 EVA1A通过调控自噬在扰动流下促进内皮细胞凋亡和炎症激活 2025-2-24
EVA1A (Eva-1 Homolog A) Promotes Endothelial Apoptosis and Inflammatory Activation Under Disturbed Flow Via Regulation of AutophagyKeywords: apoptosis; atherosclerosis; autophagy;
1644 次 EPAS1 通过内皮脂肪酸摄取减轻血流紊乱区域动脉粥样硬化的发生 2025-2-17
EPAS1 Attenuates Atherosclerosis Initiation at Disturbed Flow Sites Through Endothelial Fatty Acid UptakeKeywords: atherosclerosis; diet, high-fat; endothelial cells; obesity; plaq
1529 次 NADPH 氧化酶4在缺氧条件下介导内皮功能 2025-2-17
NADPH Oxidase 4: Crucial for Endothelial Function under Hypoxia—Complementing ProstacyclinKeywords: NADPH oxidase 4; PTGIS; endothelial function; human endothelial cells; hyp
1722 次人脐带间充质干细胞促进小胶质细胞中的细胞外基质重塑 2025-2-10
Human Umbilical Cord-Mesenchymal Stem Cells Promote Extracellular Matrix Remodeling in MicrogliaKeywords: extracellular matrix; human umbilical cord mesenchymal stem cells; microgl
1760 次 Piezo1 通道通过介导机械应力诱导的铁内流来加剧髓核细胞的铁死亡 2025-2-10
Piezo1 channel exaggerates ferroptosis of nucleus pulposus cells by mediating mechanical stress-induced iron influxSubject terms: Homeostasis, Pathogenesis机械应力可以有效地调节细胞
1384 次 B细胞前体急性淋巴细胞白血病在骨髓间充质基质中引发干扰素α/β反应 2024-12-30
B-cell precursor acute lymphoblastic leukemia elicits an interferon-α/β response in bone marrow-derived mesenchymal stromaKWS：BCP-ALL；interferon-α/β；bone m
1551 次机械力经靶向 SMAD1促巨噬细胞外泌体 UCHL3促进骨髓间充质干细胞成骨 2024-12-30
Mechanical force induces macrophage-derived exosomal UCHL3 promoting bone marrow mesenchymal stem cell osteogenesis by targeting SMAD1Keywords: Exosomes; Macrophages; Mechanical fo
1397 次人牙龈成纤维细胞的成骨分化可抑制破骨细胞形成 2024-12-23
Osteogenic Differentiation of Human Gingival Fibroblasts Inhibits Osteoclast FormationKeywords: gingival fibroblasts; osteoblasts; osteoclastogenesis; osteoclasts; osteogenesis.牙龈
1713 次循环牵张应力通过整合素αVβ3-肌动蛋白丝轴调控MSCs早期成骨分化 2024-12-23
Regulation of the integrin αVβ3- actin filaments axis in early osteogenic differentiation of human mesenchymal stem cells under cyclic tensile stressKeywords: Integrin &