Her3 His Tag Protein, Mouse

优爱(UA BIO)，国产重组蛋白专家，
产品别名: Her3 His Tag Protein, Mouse

HER3 is a member of the HER (EGFR/ErbB) receptor family consisting of four closely related type 1 transmembrane receptors (EGFR, HER2, HER3, and HER4). HER receptors are part of a complex signaling network intertwined with the Ras/Raf/MAPK, PI3K/AKT, JAK/STAT, and PKC signaling pathways. Aberrant activation of the HER receptors and downstream signaling molecules tips the balance on cellular events, leading to various types of cancers. The HER3 protein is expressed in several types of tumors. That fact, together with the role of HER3 in promoting cell proliferation, implicate that targeting HER3 may have therapeutic relevance. Furthermore, expression and activation of HER3 has been linked to resistance to drugs that target other HER receptors such as agents that act on EGFR or HER2.

优爱蛋白是优宁维集团旗下品牌，始终专注于为药物研发、细胞治疗、基因治疗及基础科研等领域提供全面的蛋白类试剂与技术服务。我们的产品涵盖药物靶点蛋白、细胞因子、工具酶、药物筛选与激酶检测试剂盒，同时承接蛋白定制表达、全长跨膜蛋白开发等高项目。