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Her2 His Tag Protein, Cynomolgus
英文名称:总访问:5
国产/进口:国产半年访问:5
产地/品牌:优爱(UA BIO)产品类别:细胞生物学试剂
规       格:100μg 最后更新:2026-1-30
货       号:UA010241
CAS   号:
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产品别名: Her2 His Tag Protein, Cynomolgus

Human Epidermal growth factor Receptor 2 (HER2) is also called ERBB2, HER-2, NEU, NGL, TKR1 and c-erb B2, and is a protein giving higher aggressiveness in breast cancers. It is a member of the ErbB protein family, more commonly known as the epidermal growth factor receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-mediated activation of downstream molecules. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on.
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