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FGF-1/FGF-Acidic Protein, Human
英文名称:总访问:1
国产/进口:国产半年访问:1
产地/品牌:优爱(UA BIO)产品类别:免疫学/诊断检测试剂
规       格:100μg 最后更新:2026-1-30
货       号:UA040032
CAS   号:
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产品别名: FGF-1/FGF-Acidic Protein, Human

Human fibroblast growth factor 1 (FGF-1), also known as acidic fibroblast growth factor (FGF-Acidic), is one of the best characterized members of the FGF superfamily. FGF-1 is a powerful mitogen that exhibit potent effects on numerous different types of cells. It plays a number of roles in several important physiological and pathological processes, such as embryonic development, morphogenesis, angiogenesis, wound healing and atheromatosis, carcinogenesis, development, and invasion of cancer. FGF-1 is released extracellularly as a disulfide-linked homodimer and is stored in complex with extracellular heparan sulfate. The association of FGF-1 with heparan sulfate is a prerequisite for its subsequent interaction with FGF receptors. Ligation triggers receptor dimerization, transphosphorylation, and internalization of receptor/FGF complexes.

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