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1077 次 拉伸诱导的内皮细胞单层损伤的相关研究 2025-6-10
Stretch-induced damage in endothelial monolayersKeywords: Aging; Cell mechanics; Endothelium; Mechanobiology; Senescence; Stretch.由于血流的脉动性，包括流体剪切力、压力和循环拉伸在
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1036 次 视网膜神经节细胞经IL-12-SCGF-β串扰诱导干细胞衍生的神经保护作用 2025-6-9
Retinal ganglion cells induce stem cell-derived neuroprotection via IL-12 to SCGF-β crosstalkKWS：Retinal ganglion cells；stem cell；neuroprotection；IL-12；SCGF-β；cross
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1254 次 血管内皮-间充质串扰通过 Notch 信号驱动人成骨细胞的成骨分化 2025-6-4
Endothelial-mesenchymal crosstalk drives osteogenic differentiation of human osteoblasts through Notch signalingKeywords: Co-culture; Endothelial cells; Notch signaling; Osteoblast
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1176 次 TRPV4 抑制剂和机械负荷对减轻炎症的协同作用 2025-6-3
Synergetic role of TRPV4 inhibitor and mechanical loading on reducing inflammationKeywords: anti-inflammatory phenotype; inhibition, mechanical loading; macrophage polarization; mi
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1141 次 I 类 PI3Ks 激活小梁网细胞中拉伸诱导的自噬 2025-5-27
Class I PI3Ks activate stretch-induced autophagy in trabecular meshwork cellsKeywords: Autophagy; Glaucoma; Mechanical stress; PI3K; Primary cilia; Trabecular meshwork.眼压升高（IO
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979 次 内皮 IGFBP6 抑制血管炎症和动脉粥样硬化 2025-5-26
Endothelial IGFBP6 suppresses vascular inflammation and atherosclerosisKWS：IGFBP6；vascular inflammation；atherosclerosis动脉粥样硬化通常发生在血流紊乱（DF）区域，例如动脉分支或弯
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1164 次 c-REL串扰TXNIP-p38与非经典NF-κB通路协调紊乱血流区动脉粥样硬化 2025-5-20
Endothelial c-REL orchestrates atherosclerosis at regions of disturbed flow through crosstalk with TXNIP-p38 and non-canonical NF-κB pathwaysKWS：c-REL, Shear stress, Endothe
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1354 次 动脉粥样硬化中血流诱导的内皮细胞重编程 2025-5-19
Flow-induced reprogramming of endothelial cells in atherosclerosisSubject terms: Cell biology, Systems biology动脉粥样硬化是一种主要影响动脉的多因素慢性炎症性疾病。内皮细胞功能障碍
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1312 次 E2F1诱导IL-6炎症循环介导癌症免疫，预测T细胞表型转换和治疗反应 2025-5-13
E2F1-induced autocrine IL-6 inflammatory loop mediates cancer-immune crosstalk that predicts T cell phenotype switching and therapeutic responsivenessKeywords: CD4 +/CD8 + T cells;
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1179 次 IL-33 经 OX40L 促进人肥大细胞诱导 CD4+ T 细胞产生 IL-9 2025-5-12
IL-33-primed human mast cells drive IL-9 production by CD4+ effector T cells in an OX40L-dependent mannerKeywords: IL-33; IL-9; OX40L; Th cell; mast cell.2 型免疫反应是针对皮肤和粘
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1435 次 运动减轻血流再循环激活代谢转能器 SCD1 催化血管保护性代谢物 2025-5-7
Exercise mitigates flow recirculation and activates metabolic transducer SCD1 to catalyze vascular protective metabolitesKS：Exercise；flow recirculation；SCD1作为对周期性心脏收缩的
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1787 次 靶向软骨下骨骨细胞中的H19用于减轻骨关节炎软骨降解 2025-5-6
Targeting Long Noncoding RNA H19 in Subchondral Bone Osteocytes and the Alleviation of Cartilage Degradation in OsteoarthritisKWS：LncRNA H19；Subchondral Bone Osteocytes；Cartilag
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1195 次 内皮雌激素-心肌cGMP轴决定压力超负荷期间的血管生成和心脏功能 2025-4-28
Endothelial oestrogen-myocardial cyclic guanosine monophosphate axis critically determines angiogenesis and cardiac performance during pressure overloadKeywords: Angiogenesis; Cycl
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1140 次 机械拉伸诱导的活性氧驱动新生猪肾上皮细胞内皮素的产生 2025-4-27
Induction of reactive oxygen species by mechanical stretch drives endothelin production in neonatal pig renal epithelial cellsKeywords: Acute kidney injury; Endothelin; Endothelin
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1240 次 Hes1/Piezo1 通路在糖皮质激素诱导的骨质疏松症中的关键作用 2025-4-22
The pivotal role of the Hes1/Piezo1 pathway in the pathophysiology of glucocorticoid-induced osteoporosisKeywords: Bone biology; Bone disease; Osteoporosis; Therapeutics.糖皮质激素
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1414 次 大脑通过 PGE2 骨内感受调节负重骨：踝关节骨性关节炎和疼痛的影响 2025-4-21
Brain regulates weight bearing bone through PGE2 skeletal interoception: implication of ankle osteoarthritis and painSubject terms: Bone, Pathogenesis内感受（Interoception）是一种监
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1283 次 Piezo1 介导的星状细胞活化导致小鼠压力诱导的胰腺纤维化 2025-4-15
Piezo1-mediated stellate cell activation causes pressure-induced pancreatic fibrosis in miceKeywords: Fibrosis; Gastroenterology.慢性胰腺炎是一种胰腺组织进行性炎症性疾病，其特征是产
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1443 次 Piezo1 通道调控结膜上皮细胞 IL表达:机械应力与眼部炎症关联研究 2025-4-14
Mechanoreceptor Piezo1 channel-mediated interleukin expression in conjunctival epithelial cells: Linking mechanical stress to ocular inflammationKeywords: CREB; Conjunctival epithe
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1200 次 骨肉瘤与巨噬细胞相互作用的IL-8经 FAK 促进瘤生长转移 2025-4-8
Pivotal role of IL-8 derived from the interaction between osteosarcoma and tumor-associated macrophages in osteosarcoma growth and metastasis via the FAK pathwaySubject terms: Bone
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1331 次 NETosis 驱动高血压患者血压升高和血管功能障碍 2025-4-7
NETosis Drives Blood Pressure Elevation and Vascular Dysfunction in HypertensionKeywords: extracellular traps; histones; hypertension; neutrophils; protein-arginine deiminase type