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1352 次 紊乱血流诱导自噬并损伤自噬流以扰乱线粒体稳态 2025-9-3
Disturbed Flow Induces Autophagy, but Impairs Autophagic Flux to Perturb Mitochondrial HomeostasisKeywords: OSS; PSS; Autophagy ; Autophagic flux; Mitochondrial homeostasis.自噬是一
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1752 次 机械超负荷经 Piezo1 促进钙内流诱导GPX4 调节的软骨细胞铁死亡 2025-9-3
Mechanical overloading induces GPX4-regulated chondrocyte ferroptosis in osteoarthritis via Piezo1 channel facilitated calcium influxKeywords: Chondrocytes, Osteoarthritis, Ferropt
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1515 次 机械牵张通过机械激活的阳离子通道 Piezo1 促进增生性瘢痕的形成 2025-8-19
Mechanical stretch promotes hypertrophic scar formation through mechanically activated cation channel Piezo1Subject terms: Cell signalling, Mechanisms of disease增生性瘢痕（HS）是皮
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1197 次 RGC-32缺失可保护内皮细胞免受炎症损伤并减轻动脉粥样硬化 2025-8-19
RGC-32 deficiency protects endothelial cell from inflammation and attenuates atherosclerosisKeywords: response gene to complement 32, atherosclerosis, endothelial cells, adhesion m
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657 次 纳他霉素单克隆抗体的制备、性能及应用 2025-8-15
纳他霉素（Natamycin，NTM）是一种多烯大环内酯类抗真菌剂，广泛用于食品防腐（如奶酪、烘焙食品）和医药领域（治疗真菌感染），但其过量使用可能导致过敏反应或残留风险，因此需对其含量进行严
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1154 次 人参皂苷 Rb1 调控 SIRT1/caveolin-1/eNOS 通路防血管内皮衰老 2025-8-14
Ginsenoside Rb1 prevents age-related endothelial senescence by modulating SIRT1/caveolin-1/enos signaling pathwayKeywords: Ginsenoside Rb1, Senescence, Caveolin-1, Deacetylation, H
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1501 次 血管衰老中调控内皮细胞衰老的因素与通路 2025-8-12
Factors and Pathways Modulating Endothelial Cell Senescence in Vascular AgingKeywords: age-related vascular disease; cellular senescence; endothelial cell; molecular player; putati
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1113 次 内皮细胞中的 Rap1 可限制炎症信号传导，从而抑制动脉粥样硬化的进展 2025-8-7
Endothelial Rap1 restricts inflammatory signaling to protect from the progression of atherosclerosis.Keywords: Cardiovascular disease, Endothelial function, Hemodynamics, Inflammat
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1258 次 癌症力学生物学的进展：转移、力学与材料 2025-8-6
Advances in cancer mechanobiology: Metastasis, mechanics, and materialsKeywords: tumor microenvironment, shear stress, tension and strain, solid stress and compression, bioengineer
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917 次 睡眠压力的线粒体起源及大脑中分子变化与睡眠需求的关联 2025-8-4
熬的不是夜，是'偷来'的短暂自由""白天归顺于生活，晚上臣服于灵魂线粒体：哈？人！关掉你的网抑云，我要裂了......Section.01人为什么会睡觉？你有没有想过，我们为什么会睡
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1491 次 层流剪切应力经 miR-29b-3p/CX3CL1 轴减单核细胞黏附及动脉粥样硬化 2025-8-1
Laminar shear stress alleviates monocyte adhesion and atherosclerosis development via miR-29b-3p/CX3CL1 axis regulationKeywords: Laminar shear stress, Atherosclerosis, CX3CL1, Mono
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839 次 机械敏感型 miR 在内皮细胞对切应力和氧化还原状态响应中的作用 2025-7-31
Mechanosensitive microRNAs - Role in Endothelial Responses to Shear Stress and Redox StateKeywords: Endothelium, Shear Stress, miR, KLF2, Oxidative Stress, Inflammation血管内皮细胞
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1166 次 Piezo1调控的内皮 KDM5B参与紊乱血流诱导的动脉粥样硬化斑块形成 2025-7-24
Endothelial KDM5B Regulated by Piezo1 Contributes to Disturbed Flow Induced Atherosclerotic Plaque FormationKeywords: atherosclerosis, disturbed flow, endothelial cells, KDM5B, Pie
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1101 次 Piezo1 调控的内皮 KDM5B 参与紊乱血流诱导的动脉粥样硬化斑块形成 2025-7-22
Endothelial KDM5B Regulated by Piezo1 Contributes to Disturbed Flow Induced Atherosclerotic Plaque FormationKeywords: atherosclerosis, disturbed flow, endothelial cells, KDM5B, Pie
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1685 次 LongGene荧光定量PCR助力中科大团队荣登Nature子刊 2025-7-18
综合性Top期刊中科大发表成果近日，中国科学技术大学鲍坚强课题组，联合山东大学刘洪彬课题组，在Cell Death & Differentiation发表题为Combinatorial tagging generates a multi-purpose k
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1208 次 KLF4 和 AMPK 在内皮细胞中脉动切应力抑制糖酵解过程中的作用 2025-7-16
Roles of KLF4 and AMPK in the inhibition of glycolysis by pulsatile shear stress in endothelial cellsKeywords: AMPK; KLF4; epigenetics; GCKR; glycolysis.内皮细胞覆盖动脉管腔并直接接
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1288 次 拉伸通过增强成纤维细胞中内皮素受体B和TRPC3 的表达来促进伤口收缩 2025-7-15
Stretching Promotes Wound Contraction Through Enhanced Expression of Endothelin Receptor B and TRPC3 in FibroblastsKeywords: Stretching; Wound contraction; Endothelin Receptor B; T
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1008 次 压力响应型 miRNA - 5703 的过表达抑制压力诱导的肝癌生长和转移 2025-7-9
Overexpression of pressure-responsive miRNA-5703 inhibits pressure-induced growth and metastasis of liver cancerKeywords: liver cancer; metastasis; miRNA-5703; portal hypertension;
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1208 次 成纤维细胞中张力敏感的 HOX 基因表达用于差异瘢痕形成 2025-7-8
Tension-sensitive HOX gene expression in fibroblasts for differential scar formationKeywords: Scar formation, Hypertrophic scar; Keloid; Wound healing; Tension; Tension change; Ten
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1252 次 C/EBPβ 拮抗剂诱导巨噬细胞促炎极化增强抗肿瘤免疫 2025-7-3
The C/EBPβ antagonist peptide lucicebtide (ST101) induces macrophage polarization toward a pro-inflammatory phenotype and enhances anti-tumor immune responsesKeywords: C/EBP&b